Certain proteins just happen to be one feature that several major Dementia varieties have in common. The excess of proteins in the human brain or even protein fragments that have taken on abnormal forms are considered to be toxic to human brain cells. Some of the protein abnormalities have even been found in the cerebrospinal fluid!
The National Institute of Health, the NIH, have funded research projects designed to better understand the toxic effects of these proteins; why the buildup of proteins happen and how they can be related to the development of Alzheimer’s disease, AD and other such unrelated types of Dementia.
NINDS specifies one example on their website as being an abnormally high accumulation of beta-amyloid protein in the brain is a hallmark of AD. NINDS-funded researchers are determining which neural pathways are affected by beta-amyloid and contribute to the development of Alzheimer’s pathology and symptoms. NINDS funding also led to a genetically engineered rat model of AD that has the full array of brain changes associated with the human disease and may be used to better define causes and effects of AD related to beta-amyloid accumulation. Funding was also provided by the NIA, the National Institute of Mental Health (also part of NIH), and other organizations.
Learning about how proteins affect the human brain gives caregivers the upper edge; allowing them to simply display the fact that With Age Comes Respect.